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Withaferin A
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Withaferin A : ウィキペディア英語版
Withaferin A

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Withaferin A is a steroidal lactone which binds to and inhibits vimentin. It was first isolated from Winter cherry (''Withania somnifera''). and is the first member of the withanolides to be discovered. Withaferin A is a potent inhibitor of angiogenesis (the formation of new blood vessels).〔 Withaferin A inhibits both NF-κB and Sp1 Transcription factor activity. Withaferin A also down regulates VEGF gene expression〔 and can affect calcium signalling.
== References ==



抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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